The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

Jul. 22, 2019
Applicant:

Nikon Corporation, Tokyo, JP;

Inventors:

Eric Peter Goodwin, Oro Valley, AZ (US);

Wan Qin, Oro Valley, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01B 9/02 (2006.01); G01B 9/04 (2006.01); G01N 21/45 (2006.01); G02B 21/34 (2006.01); G03H 1/00 (2006.01); G03H 1/04 (2006.01);
U.S. Cl.
CPC ...
G01B 9/02098 (2013.01); G01B 9/04 (2013.01); G01N 21/453 (2013.01); G02B 21/34 (2013.01); G03H 1/0005 (2013.01); G03H 1/0443 (2013.01); G03H 2001/005 (2013.01); G03H 2001/0447 (2013.01);
Abstract

Object interference in biological samples generated by lateral shearing interference microscopes is addressed by a shearing microscope slide comprising a periodic structure having alternating reference and sample regions. In some embodiments, the reference regions are configured to provide references that remove sample overlap in a sheared microscopic measurement. A system for generating sheared microscopic measurements is also provided that comprises an inlet configured to receive a sample material, an outlet configured to release a portion of the sample material, and a periodic structure having a plurality of interleaved reference and sample channels. In some cases, the sample channels are configured to accommodate a flow of sample material from the inlet to the outlet and the reference channels are configured to provide references that remove sample overlap in a sheared microscopic measurement.


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