The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2022
Filed:
Jul. 02, 2020
Tron-translationale Onkologie an Der Universitätsmedizin Der Johannes Gutenberg-universität Mainz Ggmbh, Mainz, DE;
Biontech SE, Mainz, DE;
Ugur Sahin, Mainz, DE;
Sebastian Kreiter, Mainz, DE;
Mustafa Diken, Mainz, DE;
Jan Diekmann, Mainz, DE;
Michael Koslowski, Oberschleißheim, DE;
Cedrik Britten, Mainz, DE;
John Christopher Castle, Mainz, DE;
Martin Löwer, Mainz, DE;
Bernhard Renard, Mainz, DE;
Tana Omokoko, Mainz, DE;
Johannes Hendrikus De Graaf, Lorzweiler, DE;
Abstract
The present invention relates to the provision of vaccines which are specific for a patient's tumor and are potentially useful for immunotherapy of the primary tumor as well as tumor metastases. In one aspect, the present invention relates to a method for providing an individualized cancer vaccine comprising the steps: (a) identifying cancer specific somatic mutations in a tumor specimen of a cancer patient to provide a cancer mutation signature of the patient; and (b) providing a vaccine featuring the cancer mutation signature obtained in step (a). In a further aspect, the present invention relates to vaccines which are obtainable by said method.