The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2022
Filed:
Dec. 21, 2017
Omniome, Inc., San Diego, CA (US);
Corey M. Dambacher, La Jolla, CA (US);
Devon Cayer, Del Mar, CA (US);
Richard LeCoultre, San Diego, CA (US);
Joseph Rokicki, San Diego, CA (US);
Kerry Wilson, La Jolla, CA (US);
Eugene Tu, San Diego, CA (US);
Kandaswamy Vijayan, San Diego, CA (US);
OMNIOME, INC., San Diego, CA (US);
Abstract
Method of identifying a cognate nucleotide (i.e., the 'next correct nucleotide') for a primed template nucleic acid molecule. In some embodiments, an ordered or random array of primed target nucleic acids characterized by different cognate nucleotides can be evaluated using a single imaging step to identify different cognate nucleotides for a collection of different primed template nucleic acid molecules. An optional incorporation step can follow the identifying step. A polymerase different from the ones used in the binding and examination steps can be used to incorporate a nucleotide, such as a reversible terminator nucleotide, preliminary to identification of the next cognate nucleotide.