The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2022
Filed:
Dec. 21, 2017
Applicant:
The Jackson Laboratory, Bar Harbor, ME (US);
Inventor:
James Keck, Sacramento, CA (US);
Assignee:
The Jackson Laboratory, Bar Harbor, ME (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); A01K 67/027 (2006.01); G01N 33/50 (2006.01); C07K 14/55 (2006.01); C07K 14/705 (2006.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
C12N 15/8509 (2013.01); A01K 67/0271 (2013.01); A01K 67/0278 (2013.01); C07K 14/55 (2013.01); C07K 14/70596 (2013.01); C12N 5/0663 (2013.01); G01N 33/5088 (2013.01); A01K 2207/12 (2013.01); A01K 2207/15 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01); A01K 2267/0362 (2013.01); A01K 2267/0387 (2013.01); C12N 2015/8518 (2013.01);
Abstract
The invention described herein provides non-HLA matched humanized mouse model (e.g., NSG mouse model) with patient-derived xenograft (PDX), as well as methods of making and using the same.