The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

Oct. 11, 2016
Applicant:

Molecular Templates, Inc., Georgetown, TX (US);

Inventors:

Eric Poma, New York, NY (US);

Erin Willert, Round Rock, TX (US);

Jason Kim, Austin, TX (US);

Jack Higgins, Georgetown, TX (US);

Jensing Liu, Round Rock, TX (US);

Rodney Flores-Lefranc, Round Rock, TX (US);

Assignee:

Molecular Templates, Inc., Austin, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01); C07K 16/28 (2006.01); C07K 14/25 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 39/00 (2006.01); C07K 16/18 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 19/00 (2013.01); A61K 38/164 (2013.01); A61K 38/177 (2013.01); A61K 38/1764 (2013.01); A61K 39/0011 (2013.01); A61K 39/001124 (2018.08); A61P 35/00 (2018.01); C07K 14/25 (2013.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); C07K 16/2887 (2013.01); C07K 2317/35 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); C07K 2319/01 (2013.01); C07K 2319/03 (2013.01); C07K 2319/033 (2013.01); C07K 2319/55 (2013.01); C07K 2319/70 (2013.01);
Abstract

Provided herein are multivalent CD20-binding molecules, and compositions thereof, for use in selective killing of specific cell types and/or as therapeutics for the treatment of a variety of diseases, including cancer, tumors, and immune disorders. Certain multivalent CD20-binding molecules can be used to deliver agents into CD20-expressing cells, collecting diagnostic information, and/or monitoring the treatment of diseases, such as cancers, tumors, and immune disorders.


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