The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

Sep. 10, 2019
Applicants:

Vib Vzw, Ghent, BE;

Universiteit Gent, Ghent, BE;

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Trustees of Dartmouth College, Hanover, NH (US);

Inventors:

Xavier Saelens, Ypres, BE;

Bert Schepens, Drongen, BE;

Iebe Rossey, Gentbrugge, BE;

Barney Graham, Rockville, MD (US);

Jason McLellan, Norwich, VT (US);

Morgan Gilman, White River Junction, VT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61P 31/14 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1027 (2013.01); A61K 39/12 (2013.01); A61P 31/14 (2018.01); A61K 2039/505 (2013.01); A61K 2039/55561 (2013.01); C07K 2317/22 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/76 (2013.01); C12N 2760/18534 (2013.01);
Abstract

The present invention relates to immunoglobulin single variable domains (ISVDs) that are directed against respiratory syncytial virus (RSV). More specifically, it relates to ISVDs that bind to the prefusion form of the fusion (F) protein of RSV. The invention relates further to the use of these ISVDs for prevention and/or treatment of RSV infections, and to pharmaceutical compositions comprising these ISVDs.


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