The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

Jul. 21, 2017
Applicants:

University of Utah Research Foundation, Salt Lake City, UT (US);

The Walter and Eliza Hall Institute of Medical Research, Parkville, AU;

Inventors:

John Gerbrandt Tasman Menting, Bulleen, AU;

Brian Smith, Bundoora, AU;

Danny Hung-Chieh Chou, Salt Lake City, UT (US);

Helena Safavi-Hemami, Salt Lake City, UT (US);

Michael Colin Lawrence, Newport, AU;

Baldomero M. Olivera, Salt Lake City, UT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/62 (2006.01); G16B 15/00 (2019.01); C30B 29/58 (2006.01); C30B 7/02 (2006.01); C07K 14/435 (2006.01); A61K 38/00 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/62 (2013.01); C07K 14/43509 (2013.01); C30B 7/02 (2013.01); C30B 29/58 (2013.01); G16B 15/00 (2019.02); A61K 38/00 (2013.01); A61P 3/10 (2018.01); C07K 2299/00 (2013.01);
Abstract

The present invention relates to insulin analogs, particularly insulin analogs having shortened B chains. The present invention also relates to the crystal structure of insulin from the venom of cone snails and to methods of using the crystal and related structural information to screen for and design insulin analogs that interact with or modulate the insulin receptor. The present invention also relates to therapeutic and prophylactic methods using insulin analogs.


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