The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

Jul. 26, 2018
Applicants:

Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, CN;

Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Xin Li, Shanghai, CN;

Wei He, Shanghai, CN;

Yang Chen, Shanghai, CN;

Feng He, Shanghai, CN;

Weikang Tao, Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 241/36 (2006.01); C07D 487/00 (2006.01); A61K 31/495 (2006.01); C07D 487/04 (2006.01); A61P 31/12 (2006.01); A61K 31/4985 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4985 (2013.01); A61P 31/12 (2018.01);
Abstract

The present invention relates to a piperazine heteroaryl derivative, a preparation method therefor and the use of same in medicine. In particular, the present invention relates to the piperazine heteroaryl derivative as shown in the general formula (I), a preparation method therefor, a pharmaceutical composition comprising the derivative, and the use of same as a capsid protein inhibitor, in particular in the prevention and/or treatment of diseases such as hepatitis B, influenza, herpes, AIDS, etc. The definitions of each group in the general formula (I) are the same as those defined in the description.


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