The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

May. 16, 2014
Applicant:

Surmodics, Inc., Eden Prairie, MN (US);

Inventors:

Joram Slager, St. Louis Park, MN (US);

Dale G. Swan, St. Louis Park, MN (US);

Darin DuMez, Minneapolis, MN (US);

Joseph Ventura, Elk Grove, CA (US);

Shannon Wadman, Minneapolis, MN (US);

Joseph Schmidt McGonigle, Minneapolis, MN (US);

Robert W. Hergenrother, Eden Prairie, MN (US);

Assignee:

Surmodics, Inc., Eden Prairie, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/32 (2006.01); A61L 29/04 (2006.01); A61L 29/08 (2006.01); A61K 31/337 (2006.01); A61K 31/436 (2006.01); A61M 25/10 (2013.01); A61L 29/16 (2006.01); A61K 47/34 (2017.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61L 29/041 (2013.01); A61K 31/337 (2013.01); A61K 31/436 (2013.01); A61K 47/34 (2013.01); A61L 29/085 (2013.01); A61L 29/16 (2013.01); A61M 25/10 (2013.01); A61K 9/0019 (2013.01); A61L 2300/416 (2013.01); A61L 2300/62 (2013.01); A61L 2300/63 (2013.01); A61L 2400/06 (2013.01); A61L 2420/06 (2013.01); A61L 2420/08 (2013.01); A61M 2025/105 (2013.01);
Abstract

Disclosed herein is a delivery composition for administering a hydrophobic active agent. In one embodiment, a delivery composition for local administration of a hydrophobic active agent to a tissue or organ of a patient is disclosed. In one embodiment, the delivery composition includes a cationic delivery agent, a therapeutically effective amount of a hydrophobic active agent and a pharmaceutically acceptable aqueous carrier. In one embodiment, the cationic delivery agent includes polyethyleneimine (PEI). In an embodiment, the invention includes a drug delivery device including a substrate; and coated therapeutic agent particles disposed on the substrate, the coated therapeutic agent particles comprising a particulate hydrophobic therapeutic agent; and a vinyl amine polymer. Methods of making the delivery composition, as well as kits and methods of use are also included herein.


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