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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11246939 B1

PDFFull Text
Date of Patent:
Feb. 15, 2022

Filed:

Sep. 17, 2019

Immunoregulatory protein-sirna complex having anticancer activity

Applicant:

Korea Institute of Science and Technology, Seoul, KR;

Inventors:

Sun Hwa Kim, Seoul, KR;

Ick Chan Kwon, Seoul, KR;

In-San Kim, Seoul, KR;

Kwangmeyung Kim, Seoul, KR;

Yoosoo Yang, Seoul, KR;

Young-Ji Ko, Seoul, KR;

Assignee:

Korea Institute of Science and Technology, Seoul, KR;

Attorneys:

Foley Hoag LLP

Dana Gordon

Mohanad Mossalam

Primary Examiner:

Sudhakar Katakam

Assistant Examiner:

Zachary J Miknis

Int. Cl.
CPC ...
A61K 47/55 (2017.01); A61K 47/54 (2017.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01); C07K 14/705 (2006.01); A61P 35/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/55 (2017.08); A61K 31/713 (2013.01); A61K 47/549 (2017.08); A61P 35/00 (2018.01); C07K 14/70596 (2013.01); C12N 15/1138 (2013.01); A61K 38/00 (2013.01); C12N 2310/3513 (2013.01);
Abstract

A fusion protein-siRNA complex according to the present disclosure binds specifically to cancer cells, is taken up effectively by the cells, and exhibits anticancer activity as it is degraded by lysosomes. The fusion protein-siRNA complex provides maximized anticancer activity so that the cancer cells can be removed by autoimmunity, by inhibiting the immunity of the cancer cells and enhancing phagocytosis by macrophages.

Find Patent Forward Citations

Kim, Sun. (2022). Immunoregulatory protein-sirna complex having anticancer activity (U.S. Patent No. 11246939). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11246939

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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