The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

May. 10, 2017
Applicant:

Merck Patent Gmbh, Darmstadt, DE;

Inventors:

Dieter Lubda, Bensheim, DE;

Mengyao Zheng, Bensheim, DE;

Nicole Di Gallo, Bensheim, DE;

Anja-Nadine Knuettel, Mannheim, DE;

Assignee:

MERCK PATENT GMBH, Darmstadt, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/32 (2006.01); A61K 45/06 (2006.01); B29C 48/00 (2019.01); C08L 29/04 (2006.01); A61K 9/14 (2006.01); C08K 5/00 (2006.01); B29K 29/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/32 (2013.01); A61K 9/146 (2013.01); A61K 45/06 (2013.01); B29C 48/022 (2019.02); C08K 5/005 (2013.01); C08K 5/0016 (2013.01); C08L 29/04 (2013.01); B29K 2029/04 (2013.01); C08L 2203/02 (2013.01);
Abstract

An extrudable polyvinyl alcohol (PVA) powder with improved flowability containing particles of PVA, which has been cryo-milled, and which has dparticle sizes in the range of 45 to 1400 μm; or which has a particle size distribution of d=20±10 μm, d=30±10 μm, d=70±10 μm, d=200±30 μm, and d=300±30 μm; and a powdery composition for the preparation of pharmaceutical formulations which contains the polyvinyl alcohol homogeneously mixed with at least one active pharmaceutical ingredient (API); and a process for producing a solid pharmaceutical dosage form by extruding or forming a homogeneous melt of a mixture of ingredients containing the powdered polyvinyl alcohol and at least one active pharmaceutical ingredient (API), and forming a powder or a molded form.


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