The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2022
Filed:
Apr. 01, 2019
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Tzuhua Dennis Lin, Palo Alto, CA (US);
Stuart B. Goodman, Los Altos, CA (US);
Sai-Wen Tang, San Mateo, CA (US);
Everett Hurteau Meyer, Belmont, CA (US);
Magdiel Pérez Cruz, San Mateo, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 47/68 (2017.01); A61P 3/10 (2006.01); A61K 39/00 (2006.01); C07K 14/54 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 47/6849 (2017.08); A61P 3/10 (2018.01); C07K 14/5406 (2013.01); C07K 16/28 (2013.01); A61K 2039/5156 (2013.01);
Abstract
Mesenchymal stromal cells are engineered to express a chimeric antigen receptor (CAR), that specifically binds a marker of activated myeloid cells, including without limitation folate receptor beta; and are administered to an individual for treatment of inflammation at sites characterized by the presence of activated myeloid cells.