The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2022
Filed:
Sep. 29, 2017
Applicant:
Academia Sinica, Taipei, TW;
Inventors:
Assignee:
Academia Sinica, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7105 (2006.01); A61K 9/00 (2006.01); C07K 16/28 (2006.01); C12N 15/113 (2010.01); A61K 48/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7105 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 48/00 (2013.01); C07K 16/2863 (2013.01); C12N 15/113 (2013.01); C12N 15/1138 (2013.01); A61K 2039/505 (2013.01); C12N 2310/141 (2013.01); C12N 2320/31 (2013.01);
Abstract
Methods for ameliorating cardiac is juries such as myocardial infarction by either enhancing the activity of a let-7 microRNA or inhibiting the activity of transformation growth factor beta receptor III (T GFBR3). Also provided herein are assay methods for detecting the level of TGFBR3, the level of a let-7 microRNA, or both in a biological sample.