The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2022
Filed:
Apr. 26, 2017
Applicant:
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Inventors:
Stuart A. Aaronson, New York, NY (US);
Albino Troilo, New York, NY (US);
Erica K. Benson, New York, NY (US);
Assignee:
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); C12Q 1/6886 (2018.01); A61K 31/513 (2006.01); A61K 31/506 (2006.01); A61K 31/352 (2006.01); A61K 31/519 (2006.01); A61B 10/02 (2006.01); A61K 31/495 (2006.01); A61K 31/505 (2006.01); A61K 31/33 (2006.01); C07K 16/24 (2006.01); C07K 16/30 (2006.01); A61K 31/095 (2006.01); A61K 31/7064 (2006.01);
U.S. Cl.
CPC ...
A61K 31/513 (2013.01); A61B 10/02 (2013.01); A61K 31/095 (2013.01); A61K 31/33 (2013.01); A61K 31/352 (2013.01); A61K 31/495 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); A61K 31/7064 (2013.01); A61P 35/00 (2018.01); C07K 16/24 (2013.01); C07K 16/30 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01);
Abstract
The present invention relates to a method of treating a tumor in a subject. This method involves administering to a subject having a Hippo pathway mutant tumor a tankyrase inhibitor, where the tumor is susceptible to treatment with the tankyrase inhibitor, and said administering is carried out to treat the tumor. The present invention also relates to a method of treating cancer in a subject, and a method of identifying a subject as a candidate for treatment.