The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2022
Filed:
May. 31, 2017
Applicants:
The Procter & Gamble Company, Cincinnati, OH (US);
The Cleveland Clinic Foundation, Cleveland, OH (US);
Inventors:
Stanley Leon Hazen, Pepper Pike, OH (US);
Jose Carlos Garcia-Garcia, Cincinnati, OH (US);
George Franklin Gerberick, West Chester, OH (US);
John August Wos, Mason, OH (US);
Xiaodong Gu, Cleveland, OH (US);
Michael Reilly, Lebanon, OH (US);
Mark Robert Sivik, Mason, OH (US);
Jodie Michelle Reed, Loveland, OH (US);
David Blair Cody, West Harrison, OH (US);
Assignees:
The Procter & Gamble Company, Cincinnati, OH (US);
The Cleveland Clinic Foundation, Cleveland, OH (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/14 (2006.01); C07D 303/36 (2006.01); A61K 31/275 (2006.01); C07C 237/06 (2006.01); A61K 31/04 (2006.01); C07C 229/30 (2006.01); C07C 217/40 (2006.01); C07D 211/46 (2006.01); C07C 215/40 (2006.01); C07C 229/12 (2006.01); C07C 219/08 (2006.01); C07D 451/02 (2006.01); A61K 31/205 (2006.01); C07C 255/24 (2006.01); C07C 211/63 (2006.01); C07C 229/22 (2006.01); C07C 11/02 (2006.01); C07C 11/22 (2006.01); C07C 13/04 (2006.01); C07C 69/003 (2006.01); C07C 69/01 (2006.01); C07C 211/62 (2006.01); C07C 233/02 (2006.01); C07C 255/07 (2006.01); C07D 303/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/14 (2013.01); A61K 31/04 (2013.01); A61K 31/205 (2013.01); A61K 31/275 (2013.01); C07C 11/02 (2013.01); C07C 11/22 (2013.01); C07C 13/04 (2013.01); C07C 69/003 (2013.01); C07C 69/01 (2013.01); C07C 211/62 (2013.01); C07C 211/63 (2013.01); C07C 215/40 (2013.01); C07C 217/40 (2013.01); C07C 219/08 (2013.01); C07C 229/12 (2013.01); C07C 229/22 (2013.01); C07C 229/30 (2013.01); C07C 233/02 (2013.01); C07C 237/06 (2013.01); C07C 255/07 (2013.01); C07C 255/24 (2013.01); C07D 211/46 (2013.01); C07D 303/04 (2013.01); C07D 303/36 (2013.01); C07D 451/02 (2013.01); C07C 2601/02 (2017.05);
Abstract
A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO by providing a composition comprising a compound set forth in Formula (I):