The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

May. 12, 2017
Applicant:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

Hyun Koo, Philadelphia, PA (US);

Henry Daniell, Media, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 1/02 (2006.01); A61K 9/68 (2006.01); A61K 8/64 (2006.01); A61P 31/04 (2006.01); A01N 43/40 (2006.01); A01N 65/38 (2009.01); A61K 8/02 (2006.01); A61K 8/21 (2006.01); A61K 8/49 (2006.01); A61K 8/66 (2006.01); A61K 9/00 (2006.01); A61K 38/16 (2006.01); A61K 38/47 (2006.01); A61Q 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 8/645 (2013.01); A01N 43/40 (2013.01); A01N 65/38 (2013.01); A01N 65/385 (2013.01); A61K 8/0216 (2013.01); A61K 8/21 (2013.01); A61K 8/4926 (2013.01); A61K 8/66 (2013.01); A61K 9/0056 (2013.01); A61K 9/0058 (2013.01); A61K 38/168 (2013.01); A61K 38/47 (2013.01); A61P 1/02 (2018.01); A61P 31/04 (2018.01); A61Q 11/00 (2013.01); C12Y 302/01003 (2013.01); C12Y 302/01011 (2013.01); C12Y 302/01059 (2013.01);
Abstract

The invention provides a method for combating biofilm, said method comprising contacting a biofilm with a composition comprising an effective amount of antimicrobial peptide biofilm enzyme combinations, preferably in the form of a fusion protein. The biofilm may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides a composition for use in the treatment or prevention of a biofilm in a subject, particularly in the oral cavity.


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