The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

Mar. 04, 2016
Applicant:

Pormedtec Co., Ltd., Kanagawa, JP;

Inventors:

Hiroshi Nagashima, Kanagawa, JP;

Hitomi Matsunari, Kanagawa, JP;

Masahito Watanabe, Kanagawa, JP;

Assignee:

PorMedTec Co., Ltd., Kanagawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); C12N 9/10 (2006.01); C07K 14/705 (2006.01); C07K 14/47 (2006.01); C12N 5/16 (2006.01); C12N 15/877 (2010.01);
U.S. Cl.
CPC ...
A01K 67/0275 (2013.01); A01K 67/027 (2013.01); A01K 67/0271 (2013.01); A01K 67/0273 (2013.01); A01K 67/0276 (2013.01); C07K 14/4702 (2013.01); C07K 14/705 (2013.01); C12N 5/16 (2013.01); C12N 9/1018 (2013.01); C12N 15/8778 (2013.01); C12Y 201/03003 (2013.01); A01K 2227/108 (2013.01); A01K 2267/0306 (2013.01); A01K 2267/0362 (2013.01); A01K 2267/0375 (2013.01);
Abstract

Disease model pigs produced by nuclear transplantation, disease model pigs exhibiting stable phenotypes and production methods thereof are provided. Chimeric pigs for producing disease model pigs exhibiting stable phenotypes, genital glands thereof, and germ cells thereof are also provided. A method for producing a genetically modified disease model pig, includes: (a) transplanting a nucleus of a genetically modified cell into cytoplasm of an egg; (b) developing an obtained clonal embryo in a womb of a female pig to obtain an offspring; and mating the obtained offspring or having the offspring undergo sexual reproduction to further obtain the genetically modified offspring as a disease model pig.


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