The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2022

Filed:

Apr. 21, 2017
Applicants:

Université Libre DE Bruxelles, Brussels, BE;

Vrije Universiteit Brussel, Brussels, BE;

Inventors:

Eizirik Decio Laks, Dilbeek, BE;

Alexander Balhuizen, Brussels, BE;

Nick Mark Devoogdt, Eppegem-Zemst, BE;

Sam Marc Kris Aimé Massa, Hoeilaart, BE;

Luc Bouwens, Dworp, BE;

Iris Mathijs, Bambrugge, BE;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 16/40 (2006.01); B01D 15/38 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); B01D 15/3809 (2013.01); B01D 15/3823 (2013.01); C07K 16/40 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C12N 2501/734 (2013.01); G01N 2333/948 (2013.01); G01N 2800/042 (2013.01);
Abstract

The present invention is directed to the identification of a biomarker specifically located in the plasma membrane of pancreatic beta cells. Based on a set of specific features the biomarker is a unique candidate for imaging and targeting strategies to study the pancreatic beta cell mass in health and disease (T1D, T2D, pancreatic cancers, obesity, islet transplantation, beta cell regeneration).


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