The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Apr. 15, 2015
Siemens Healthineers Nederland B.v., The Hague, NL;
Coen Adrianus Verschuren, Eindhoven, NL;
Dominique Maria Bruls, Heeze, NL;
Albert Hendrik Jan Immink, Eindhoven, NL;
Femke Karina De Theije e/v Wijgergangs, Berghem, NL;
Thea van der Wijk, Bunnik, NL;
Alexander Marc Van Der Lee, Venlo, NL;
Johannes Joseph Hubertina Barbara Schleipen, Eindhoven, NL;
Siemens Healthineers Nederland B.V., The Hague, NL;
Abstract
The invention relates to a carrier with a binding surface at which target components that comprise label particles, for example magnetic particles, can collect and optionally bind to specific capture elements. An input light beam (L) is transmitted into the carrier and totally internally reflected at the binding surface. The amount of light in the output light beam (L) and optionally also of fluorescence light emitted by target components at the binding surface is then detected by a light detector. Evanescent light generated during the total internal reflection is affected (absorbed, scattered) by target components and/or label particles at the binding surface and will therefore be missing in the output light beam (L). This can be used to determine the amount of target components at the binding surface from the amount of light in the output light beam (L, L, L). A magnetic field generator is optionally used to generate a magnetic field (B) at the binding surface by which magnetic label particles can be manipulated, for example attracted or repelled.