The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Jan. 08, 2020
Applicant:
Guardant Health, Inc., Redwood City, CA (US);
Inventors:
Helmy Eltoukhy, Atherton, CA (US);
AmirAli Talasaz, Atherton, CA (US);
Darya Chudova, San Jose, CA (US);
Diana Abdueva, Orinda, CA (US);
Assignee:
GUARDANT HEALTH, INC., Redwood City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G16B 30/00 (2019.01); C12Q 1/6809 (2018.01); G16B 99/00 (2019.01); G16B 30/10 (2019.01); G16B 20/10 (2019.01); C12Q 1/6874 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 1/6809 (2013.01); C12Q 1/6874 (2013.01); G16B 20/10 (2019.02); G16B 30/00 (2019.02); G16B 30/10 (2019.02); G16B 99/00 (2019.02);
Abstract
Methods are provided herein to improve automatic detection of copy number variation in nucleic acid samples. These methods provide improved approaches for determining baseline copy number of genetic loci within a sample, reduce variation due to features of genetic loci, sample preparation, and probe exhaustion.