The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Dec. 18, 2014
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Assignee:
Novartis AG, Basel, CH;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 15/00 (2006.01); C12P 21/00 (2006.01); C07K 14/47 (2006.01); C12N 15/113 (2010.01); C12N 5/00 (2006.01); C12Q 1/6888 (2018.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); C07K 14/47 (2013.01); C07K 14/4703 (2013.01); C12N 5/00 (2013.01); C12N 15/113 (2013.01); C12Q 1/6888 (2013.01); C12N 15/907 (2013.01); C12N 2310/14 (2013.01); C12N 2510/02 (2013.01); C12N 2511/00 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The disclosure pertains to novel eukaryotic cell suitable for recombinant production of a product of interest, wherein the genome of the host cell is altered so that the effect of protein FAM60A is impaired in said cell, e.g. by reducing or eliminating functional expression of gene FAM60A thereby improving the stability characteristics. Furthermore, the present disclosure provides associated technologies wherein such host cells are used in recombinant production technologies.