The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2022

Filed:

Jun. 14, 2017
Applicants:

Advanced Biodesign, Saint-Priest, FR;

Jean-yves Quash, Gometz la Ville, FR;

Inventors:

Ismail Ceylan, Saint-Priest, FR;

Gerry Quash, Saint-Priest, FR;

Mileidys Perez-Alea, Saint-Priest, FR;

Guillaume Martin, Saint-Priest, FR;

Assignee:

ADVANCED BIODESIGN, Saint-Priest, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/00 (2006.01); C07K 16/44 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); G01N 33/558 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); G01N 33/5308 (2013.01); G01N 33/558 (2013.01); G01N 33/6893 (2013.01); C07K 2317/34 (2013.01); G01N 2410/00 (2013.01); G01N 2800/26 (2013.01);
Abstract

The present invention concerns an ex vivo method for the monitoring of apoptosis which is based on the detection of free gamma-glutamyl-L-epsilon-Lysine (GGEL) in a biological sample of a subject with a monoclonal antibody specific to GGEL. The invention also relates to the monoclonal antibody specific to GGEL, as well as to diagnostic kits containing such a ligand.


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