The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Sep. 21, 2018
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Peter Bruenker, Hittnau, CH;
Rebecca Croasdale-Wood, Preston, GB;
Christian Klein, Bonstetten, CH;
Juergen Michael Schanzer, Munich, DE;
Kay-Gunnar Stubenrauch, Penzberg, DE;
Pablo Umana, Wollerau, CH;
Martina Geiger, Obfelden, CH;
Eric Sullivan, Pleasanton, CA (US);
Jigar Patel, Pleasanton, CA (US);
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Abstract
The present invention generally relates to novel protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides. The present invention also relates to polynucleotides encoding such protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides of the invention, and to methods of using these protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides in the treatment of disease.