The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Jan. 09, 2018
Applicant:
Ardelyx, Inc., Fremont, CA (US);
Inventors:
Assignee:
ARDELYX, INC., Fremont, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61K 47/55 (2017.01); A61P 1/10 (2006.01); A61P 9/12 (2006.01); A61P 1/00 (2006.01); A61P 9/04 (2006.01); A61P 29/00 (2006.01); A61P 3/12 (2006.01); C07D 241/04 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61K 47/55 (2017.08); A61P 1/00 (2018.01); A61P 1/10 (2018.01); A61P 3/12 (2018.01); A61P 9/04 (2018.01); A61P 9/12 (2018.01); A61P 29/00 (2018.01); C07D 241/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 487/08 (2013.01);
Abstract
The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders.