The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2022

Filed:

Aug. 25, 2017
Applicant:

Curtana Pharmaceuticals, Inc., Austin, TX (US);

Inventors:

Graham Beaton, San Diego, CA (US);

Stanton F. McHardy, Waring, TX (US);

Ambrosio Lopez, Jr., San Antonio, TX (US);

Bismarck Campos, San Antonio, TX (US);

Hua-Yu Leo Wang, San Antonio, TX (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/48 (2006.01); A61P 35/00 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 239/48 (2013.01); A61P 35/00 (2018.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01);
Abstract

Described herein are urea compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular the Olig2 inhibitors may be used to treat glioblastoma.


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