The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2022

Filed:

Sep. 03, 2019
Applicant:

Basf SE, Ludwigshafen am Rhein, DE;

Inventors:

Peter Zehner, Weisenheim am Berg, DE;

Oliver Bey, Ludwigshafen am Rhein, DE;

Assignee:

BASF SE, Ludwigshafen am Rhein, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 45/62 (2006.01); C07C 29/00 (2006.01); B01J 19/00 (2006.01); B01J 19/18 (2006.01); B01J 31/24 (2006.01); C07C 29/17 (2006.01); C07C 31/04 (2006.01); C07C 33/14 (2006.01); C07C 47/21 (2006.01);
U.S. Cl.
CPC ...
C07C 45/62 (2013.01); B01J 19/0066 (2013.01); B01J 19/1837 (2013.01); B01J 31/24 (2013.01); C07C 29/177 (2013.01); C07C 31/04 (2013.01); C07C 33/14 (2013.01); B01J 2219/00033 (2013.01); B01J 2531/822 (2013.01); C07C 47/21 (2013.01);
Abstract

Process for the continuous production of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral α,β-unsaturated carbonyl compound with hydrogen in the presence of a homogeneous rhodium catalyst that has at least one chiral ligand, wherein a liquid reaction mixture comprising the prochiral α,β-unsaturated carbonyl compound is subjected in a first, backmixed reactor to a gas/liquid two-phase hydrogenation, and the liquid reaction mixture is then further hydrogenated in a second reactor, wherein the prochiral α,β-unsaturated carbonyl compound is employed in the first reactor in a concentration from 3% to 20% by weight. The process allows a high total conversion to the prochiral α,β-unsaturated carbonyl compound.


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