The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Jun. 28, 2019
Applicant:
Actinium Pharmaceuticals, Inc., New York, NY (US);
Inventors:
Kaushik Dave, Edison, NJ (US);
Shubh Sharma, Cranbury, NJ (US);
Assignee:
Actinium Pharmaceuticals, Inc., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/10 (2006.01); A61K 35/28 (2015.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01); A61K 9/00 (2006.01); A61K 47/22 (2006.01); A61K 47/32 (2006.01); A61K 47/42 (2017.01); A61K 35/12 (2015.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/1069 (2013.01); A61K 9/0019 (2013.01); A61K 35/28 (2013.01); A61K 39/39591 (2013.01); A61K 47/22 (2013.01); A61K 47/32 (2013.01); A61K 47/42 (2013.01); A61K 51/1096 (2013.01); C07K 16/289 (2013.01); C07K 16/3061 (2013.01); A61K 2035/124 (2013.01); A61K 2039/505 (2013.01); C07K 2317/51 (2013.01); C07K 2317/94 (2013.01);
Abstract
Compositions and methods are described for stabilizing a radio-iodinated monoclonal IgG antibody for up to 17 days against radiolytic decomposition. The stabilized radiolabeled murine antibody binding the CD45 antigen expressed on various forms of lymphomas is useful as a radio-therapeutic and diagnostic agent in the treatment of human malignancies of hematopoietic origin, including lymphomas.