The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Jun. 04, 2018
Applicant:
Newbio Therapeutics, Inc., Shanghai, CN;
Inventors:
Nianhe Han, Shanghai, CN;
Deqiang An, Shanghai, CN;
Di Zeng, Shanghai, CN;
Baoxiang Wang, Shanghai, CN;
Huali Li, Shanghai, CN;
Hang Chen, Shanghai, CN;
Chun Yang, Shanghai, CN;
Assignee:
NewBio Therapeutics, Inc., Shanghai, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); C07D 271/113 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6889 (2017.08); A61K 47/6803 (2017.08); A61K 47/6851 (2017.08); C07D 271/113 (2013.01); C07K 16/32 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention is directed to oxadiazole linkers and use thereof, more specifically to the compounds represented by formula I, II, and III, and their use in the preparation of antibody-drug conjugates (ADCs). The ADCs obtained from said oxadiazole linkers have high homogeneity and stability, and could be used effectively for the treatment of various diseases including tumors. The definition of the groups in formula I, II, and III is the same as that in the description.