The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Dec. 14, 2017
Tarveda Therapeutics, Inc., Watertown, MA (US);
Benoît Moreau, Newton, MA (US);
Brian H. White, Malden, MA (US);
Mark T. Bilodeau, Waltham, MA (US);
Mary Simcox, Lexington, MA (US);
Kerry Whalen, Waltham, MA (US);
Leila Alland, Bernardsville, NJ (US);
Richard Wooster, Natick, MA (US);
Rajesh R. Shinde, Lexington, MA (US);
TARVEDA THERAPEUTICS, INC., Watertown, MA (US);
Abstract
Conjugates of an active agent attached to a targeting moiety, such as an HSP90 binding moiety, via a linker, and particles comprising such conjugates have been designed. Such conjugates and particles can provide improved temporospatial delivery of the active agent, improved biodistribution and penetration in tumor, and/or decreased toxicity. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer.