The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2022

Filed:

Nov. 29, 2016
Applicant:

Regen Biopharma, Inc., La Mesa, CA (US);

Inventors:

David Koos, La Mesa, CA (US);

Thomas Ichim, San Diego, CA (US);

Assignee:

KCL Therapeutics, Inc., La Mesa, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/403 (2006.01); A61K 31/40 (2006.01); A61K 31/197 (2006.01); A61K 31/164 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/164 (2013.01); A61K 31/197 (2013.01); A61K 31/40 (2013.01); A61K 31/403 (2013.01);
Abstract

Disclosed are compounds useful for alteration of NR2F6 activity. In some embodiments of the invention compounds disclosed are utilized for stimulation of NR2F6 activity, alone, or in combination with PKC activation. In other embodiments, the invention teaches use of compounds for inhibition of NR2F6 activation. Stimulation of NR2F6 within the context of the invention is useful, intra alia, for induction of immune inhibition, or stimulation of cellular proliferation without significant induction of differentiation. Inhibition of NR2F6 is desired in situations where the practitioner of the invention seeks to augment immune response, or induce cellular differentiation. In another embodiment, inhibition of NR2F6 expression is desired in situations where inhibition of cancer or cancer stem cells is needed.


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