The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Dec. 30, 2019
Lumosa Therapeutics Co., Ltd., Taipei, TW;
Shanghai Lumosa Therapeutics Co., Ltd., Shanghai, CN;
Chan-Jung Li, Taipei, TW;
David Chih-Kuang Chou, Palo Alto, CA (US);
Jin-Ding Huang, Taipei, TW;
Shin-Jr Tsai, New Taipei, TW;
Shu-Wen Kuo, Taipei, TW;
Yu-En Tien, Taipei, TW;
Lumosa Therapeutics Co., Ltd., Taipei, TW;
Shanghai Lumosa Therapeutics Co., Ltd., Shanghai, CN;
Abstract
The present invention relates to injectable, extended-release, pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a solution comprising a pharmaceutically acceptable oil and an oil-miscible retaining solvent, as well as manufacturing processes and medical uses of the formulations. The invention further provides methods for adjusting the duration of action of the formulations by varying the ratio of the pharmaceutically acceptable oil and the oil-miscible retaining solvent.