The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2022

Filed:

Jun. 25, 2010
Applicants:

Boris P. Kovatchev, Charlottesville, VA (US);

Claudio Cobelli, Padua, IT;

Chiara Dalla Man, Venice, IT;

Inventors:

Boris P. Kovatchev, Charlottesville, VA (US);

Claudio Cobelli, Padua, IT;

Chiara Dalla Man, Venice, IT;

Assignee:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G16H 10/00 (2018.01); G16H 50/50 (2018.01); G16H 50/70 (2018.01); G06N 5/00 (2006.01); G16H 10/60 (2018.01); A61B 5/00 (2006.01); G16H 50/20 (2018.01);
U.S. Cl.
CPC ...
G16H 50/50 (2018.01); A61B 5/4842 (2013.01); A61B 5/7275 (2013.01); G06N 5/00 (2013.01); G16H 10/60 (2018.01); G16H 50/20 (2018.01); G16H 50/70 (2018.01);
Abstract

An electronic system is provided that simulates a glucose-insulin metabolic system of a T2DM or prediabetic subject, wherein the system includes a subsystem that models dynamic glucose concentration in a T2DM or prediabetic subject, including an electronic module that models endogenous glucose production (EGP(t)), or meal glucose rate of appearance (Ra(t>>, or glucose utilization (U(t)), or renal excretion of glucose (B(t)), a subsystem that models dynamic insulin concentration in said T2DM or prediabetic subject, including an electronic module that models insulin secretion (S(t)), an electronic database containing a population of virtual T2DM or prediabetic subjects, each virtual subject having a plurality of metabolic parameters, and a processing module that calculates an effect of variation of at least one metabolic parameter value on the glucose insulin metabolic system of a virtual subject by inputting the plurality of metabolic parameter values.


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