The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2022

Filed:

Jul. 23, 2015
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

Harrison Leong, San Francisco, CA (US);

Nivedita Sumi Majumdar, San Bruno, CA (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G16B 45/00 (2019.01); G16B 20/00 (2019.01); G16B 30/00 (2019.01); G16B 20/20 (2019.01); G16B 20/10 (2019.01);
U.S. Cl.
CPC ...
G16B 45/00 (2019.02); G16B 20/00 (2019.02); G16B 20/10 (2019.02); G16B 20/20 (2019.02); G16B 30/00 (2019.02);
Abstract

System and methods for the determination of a copy number of a target genomic sequence; either a target gene or genomic sequence of interest, in a biological sample are described. Various methods utilize a model drawn from a probability density function (PDF) for the assignment of a copy number of a target genomic sequence in a biological sample. Additionally, the methods provide for the determination of a confidence value for a copy number assigned to a sample based on attributes of the sample data. Additionally, various embodiments of an interactive graphical user interface (GUI) may provide an end-user with ready analysis of large sets of data representing a plurality of samples. In various embodiments of an interactive GUI, an end-user may be provided with a synchronized display of tabular and graphical sample data determined by an initial analysis according to a statistical model of a PDF. Such a synchronized display may enable an end-user to readily identify sample data for a subsequent analysis based on user input.


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