The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2022

Filed:

Nov. 12, 2017
Applicant:

Obschestvo S Ogranichennoy Otvetstvennostyu «hemacore Labs», Moscow, RU;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/86 (2006.01); G01N 21/47 (2006.01); G01N 21/64 (2006.01); G01N 33/52 (2006.01); C12Q 1/56 (2006.01);
U.S. Cl.
CPC ...
G01N 33/86 (2013.01); G01N 21/47 (2013.01); G01N 21/64 (2013.01); G01N 21/6486 (2013.01); G01N 33/52 (2013.01); C12Q 1/56 (2013.01); G01N 21/6408 (2013.01); G01N 21/6456 (2013.01); G01N 2021/6439 (2013.01); G01N 2201/062 (2013.01); G01N 2333/974 (2013.01);
Abstract

A device for monitoring the spatial and temporal dynamics of thrombin that includes a temperature-controlled sealed chamber with a transparent window and a light trap, the chamber being filled with a fluid medium and designed to accommodate a cuvette containing a test sample of blood plasma, and a coagulation activating insert placed into the cuvette, at least one illumination source and at least one first irradiation source and at least one second irradiation source capable of exciting a fluorescence signal of a special marker that forms in the sample during cleavage of a fluorogenic substrate, a camera, a pressure adjustment element capable of maintaining a pressure inside the chamber, the at least one first irradiation source provides irradiation of the sample in a direction perpendicular to the cuvette, and the at least one second irradiation source provides irradiation of the sample at an angle to the cuvette.


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