The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Dec. 01, 2017
Applicant:
Prothena Biosciences Limited, Dublin, IE;
Inventor:
Robin Barbour, Walnut Creek, CA (US);
Assignee:
PROTHENA BIOSCIENCES LIMITED, Dublin, IE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 16/18 (2006.01); G01N 21/3577 (2014.01); G01N 21/552 (2014.01); A61P 25/16 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); A61P 25/16 (2018.01); C07K 16/18 (2013.01); G01N 21/3577 (2013.01); G01N 21/552 (2013.01); C07K 2317/34 (2013.01); G01N 2333/46 (2013.01);
Abstract
The invention provides an infrared assay which allows the secondary structure analysis of alpha-synuclein from complex fluids like serum, blood plasma or cerebrospinal fluid without prior isolation, concentration or pretreatment. The secondary structure profile provides an indication of the proportion of alpha-synuclein in aggregated form and/or extent of aggregation of alpha-synuclein in aggregated form.