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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11236378 B1

PDFFull Text
Date of Patent:
Feb. 01, 2022

Filed:

Apr. 30, 2015

Method for screening drug and therapeutic targets used for treating alzheimer's disease

Applicant:

Jiangsu Nuo-beta Pharmaceutical Technology Co., Ltd., Jiangsu, CN;

Inventors:

Fude Huang, Shanghai, CN;

Xiao Zhang, Shanghai, CN;

Wenan Wang, Shanghai, CN;

Haiyan Liu, Shanghai, CN;

Assignee:

Jiangsu Nuo-Beta Pharmaceutical Technology Co. Ltd., Jiangsu, CN;

Attorney:

Goodwin Procter LLP

Primary Examiner:

Gregory S Emch

Assistant Examiner:

Aditi Dutt

Int. Cl.
CPC ...
A61P 25/28 (2006.01); C12Q 1/02 (2006.01); G01N 33/68 (2006.01); C07K 14/47 (2006.01); A01K 67/033 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/025 (2013.01); C07K 14/4711 (2013.01); G01N 33/6896 (2013.01); A01K 67/0339 (2013.01); A01K 2227/706 (2013.01); A01K 2267/0312 (2013.01); C07K 2319/02 (2013.01); G01N 2800/2821 (2013.01);
Abstract

Disclosed is the use of genetic means or a related inhibitor to inhibit and down-regulate the amount of PI4KIIIα protein, RBO/EFR3/EFR3A/EFR3B membrane proteins, TTC7 protein and membrane protein complexes formed by said proteins, or related enzyme activity to promote Aβ secretion by neuronal cells, reduce Aβ accumulation within neurons, and thereby reduce AD model fruit fly and mouse nerve dysfunction.

Find Patent Forward Citations

Huang, Fude. (2022). Method for screening drug and therapeutic targets used for treating alzheimer's disease (U.S. Patent No. 11236378). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11236378

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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