The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2022

Filed:

Apr. 20, 2017
Applicants:

Nec Solution Innovators, Ltd., Tokyo, JP;

National University Corporation Gunma University, Gunma, JP;

Inventors:

Hirotaka Minagawa, Tokyo, JP;

Katsunori Horii, Tokyo, JP;

Jou Akitomi, Tokyo, JP;

Naoto Kaneko, Tokyo, JP;

Iwao Waga, Tokyo, JP;

Masayasu Kuwahara, Maebashi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); C12Q 1/68 (2018.01); G01N 33/53 (2006.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); C12N 15/09 (2013.01); C12Q 1/68 (2013.01); G01N 33/53 (2013.01); C12N 2310/16 (2013.01); C12N 2310/333 (2013.01); C12N 2310/335 (2013.01); C12N 2310/336 (2013.01);
Abstract

The present invention provides a novel molecule that can be used for detection of sIgA. The sIgA-binding nucleic acid molecule of the present invention is characterized in that it binds to secretory immunoglobulin A (sIgA) with a dissociation constant of 37.7 nM or less, and preferably includes a polynucleotide consisting of any of base sequences of SEQ ID NOs: 1 to 12 or a partial sequence thereof, for example. According to the sIgA-binding nucleic acid molecule of the present invention, it is possible to detect sIgA in saliva.


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