The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Dec. 20, 2018
Applicant:
Genzyme Corporation, Cambridge, MA (US);
Inventor:
Carl A. Beigie, Plainville, MA (US);
Assignee:
GENZYME CORPORATION, Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/22 (2006.01); C07K 16/00 (2006.01); B01D 15/38 (2006.01); B01D 15/42 (2006.01); C07K 1/34 (2006.01); C07K 1/36 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); B01D 15/3809 (2013.01); B01D 15/426 (2013.01); C07K 1/34 (2013.01); C07K 1/36 (2013.01); C07K 16/00 (2013.01); C07K 2317/21 (2013.01); C07K 2317/52 (2013.01);
Abstract
Provided herein are methods relating to the purification of a polypeptide comprising an Fc region (e.g., an antibody) via protein A chromatography; methods relating to the use of a wash solution comprising a benzoate salt and/or benzyl alcohol during protein A chromatography; and methods of adjusting a harvest using sodium benzoate prior to protein A chromatography.