The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Mar. 27, 2017
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Fabrice Gallou, Basel, CH;
Michael Parmentier, Basel, CH;
Jianguang Zhou, Changshu/Jiangsu Province, CN;
Pengfei Guo, Changshu/Jiangsu Province, CN;
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/14 (2006.01); C07C 211/52 (2006.01); C07C 269/06 (2006.01); C07D 241/20 (2006.01); C07D 333/64 (2006.01); C07D 401/04 (2006.01); C07D 403/14 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); C07C 211/52 (2013.01); C07C 269/06 (2013.01); C07D 241/20 (2013.01); C07D 333/64 (2013.01); C07D 401/04 (2013.01); C07D 403/14 (2013.01); C07D 487/04 (2013.01);
Abstract
The present invention is directed to reaction mixtures comprising a water-surfactant mixture and a co-solvent. This technology reduced the amount of organic solvents needed for performing chemical reactions. Furthermore, compared to reaction mixtures lacking the co-solvent, solvation of the reactants and products of the chemical reaction is greatly enhanced, leading to a significantly improved yield, purity, reproducibility and robustness.