The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Jun. 29, 2017
Venenum Biodesign, Llc, Lawrence Township, NJ (US);
Chia-Yu Huang, Princeton Junction, NJ (US);
Brian F. McGuinness, Plainsboro, NJ (US);
Dongchuan Shi, Collegeville, PA (US);
Steven G. Kultgen, Hamilton, NJ (US);
Jeffrey J. Letourneau, East Windsor, NJ (US);
James R. Beasley, Doylestown, PA (US);
Philip D. Stein, Pennington, NJ (US);
Andrew G. Cole, Cranbury, NJ (US);
VENENUM BIODESIGN, LLC, Hamilton, NJ (US);
Abstract
The present invention relates to sulfonamide compounds of formula (I) and formula (II), or a pharmaceutically acceptable salt thereof. The present sulfonamide compounds are useful non-systemic TGR5 agonists that can be used to treat diabetic diseases in human. The present invention provides a pharmaceutical composition containing sulfonamide compounds of formula (I) and formula (II) and a method of making as well as a method of using same in treating patients inflicted with metabolic disorders by administering same. The compounds of the present invention may be used in combination with additional anti-diabetic drugs.