The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Apr. 28, 2014
The Johns Hopkins University, Baltimore, MD (US);
Kennedy Krieger Institute, Inc., Baltimore, MD (US);
National Institutes of Health, Bethesda, MD (US);
Michael T. McMahon, Columbia, MD (US);
Kannie Wai-Yan Chan, Baltimore, MD (US);
Michael Christopher Giano, Frederick, MD (US);
Nikita Oskolkov, Reisterstown, MD (US);
Joel Patrick Schneider, Frederick, MD (US);
Xiaolei Song, Lutherville, MD (US);
THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);
KENNEDY KRIEGER INSTITUTE, INC., Baltimore, MD (US);
NATIONAL INSTITUTES OF HEALTH, Bethesda, MD (US);
Abstract
The present invention provides novel hydrogels through peptides, which are designed to self-assemble and produce magnetic resonance (MR) contrast through chemical exchange saturation transfer (CEST). The location and integrity of these gels could consequently be tracked using MR imaging. The self-assembly of the peptides into hydrogels can be brought about by a change in pH, ionic strength, temperature, and concentration of ions.