The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Jan. 23, 2018
Applicant:
Trustees of Tufts College, Medford, MA (US);
Inventor:
Qiaobing Xu, Lexington, MA (US);
Assignee:
Trustees of Tufts College, Medford, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 47/54 (2017.01); B82Y 5/00 (2011.01); A61K 47/61 (2017.01); A61K 38/45 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6939 (2017.08); A61K 38/45 (2013.01); A61K 45/06 (2013.01); A61K 47/543 (2017.08); A61K 47/61 (2017.08); A61K 47/6907 (2017.08); B82Y 5/00 (2013.01);
Abstract
A nanocomplex, 50 to 1000 nm in size, containing a lipid-like nanoparticle formed of a cationic lipid-based compound and a modified protein formed of a protein and an anionic polymer that includes a plurality of polar groups, the lipid-like nanoparticle and the modified protein being non-covalently bonded to each other. Also disclosed are a method of preparing the above-described nanocomplex and use thereof for treating a medical condition. Further disclosed is a pharmaceutical composition containing a nanocomplex.