The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Mar. 30, 2017
Applicant:
Alteogen, Inc., Daejeon, KR;
Inventors:
Soon Jae Park, Daejeon, KR;
Hye-Shin Chung, Daejeon, KR;
Sunbae Lee, Daejeon, KR;
Minsoo Byun, Daejeon, KR;
Assignee:
ALTEOGEN, INC., Daejeon, KR;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 47/65 (2017.01); A61P 35/00 (2006.01); C07K 16/18 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); A61K 47/65 (2017.08); A61P 35/00 (2018.01); C07K 16/18 (2013.01); A61K 45/06 (2013.01);
Abstract
The present disclosure relates to an antibody-drug conjugate in which a modified antibody comprising a motif having a specific structure at the end of the antibody is conjugated to a drug via a linker, and a composition comprising the same, and more particularly to a modified antibody-drug conjugate (mADC) comprising a modified antibody that has a significantly increased conjugation yield of drug due to a motif bound to the heavy chain or light chain C-terminus of the antibody, and to a composition comprising the same.