The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Sep. 14, 2015
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Jon Lindstrom, Radnor, PA (US);
Jie Luo, Dresher, PA (US);
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, Philadelphia, PA (US);
Abstract
In one embodiment a vaccine composition comprises two or three AChR subunit constructs and an adjuvant. In some embodiments the AChR subunit construct is an AChR α1 subunit construct, an AChR β1 subunit construct, an AChR γ subunit construct, an AChR δ subunit construct, or an AChR ε subunit construct. In another embodiment, the invention provides a method of treating myasthenia gravis in a patient in need thereof, comprising administering a vaccine composition comprising one or more acetylcholine receptor subunit constructs selected from the group consisting of AChR α1 subunit, AChR β1 subunit, AChR γ subunit, AChR δ subunit, AChR ε subunit, a fragment thereof, and a combination thereof, and an adjuvant.