The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Jun. 16, 2017
Applicant:
Alexion Pharmaceuticals, Inc., Boston, MA (US);
Inventors:
Andrew Hutchinson, Stamford, CT (US);
John V. W. Reynders, Newton, MA (US);
Guillermo del Angel, Lexington, MA (US);
Nina Jain, North Andover, MA (US);
Christen D. Forbes, North Haven, CT (US);
Xiao-Qin Ren, North Attleboro, MA (US);
Barbara Burton, Chicago, IL (US);
Assignee:
Alexion Pharmaceuticals, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); A61K 38/46 (2006.01); C12N 9/20 (2006.01); A61P 1/02 (2006.01); A61P 1/16 (2006.01); C12Q 1/6853 (2018.01); C12Q 1/6858 (2018.01); C40B 40/08 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A61P 1/02 (2018.01); A61P 1/16 (2018.01); C12N 9/20 (2013.01); C12Q 1/6853 (2013.01); C12Q 1/6858 (2013.01); C12Q 1/6883 (2013.01); C12Y 301/01013 (2013.01); C12Q 2600/156 (2013.01); C12Y 301/01003 (2013.01); C40B 40/08 (2013.01);
Abstract
Compositions and methods relating to potentially pathogenic mutations in the nucleotide sequence of a human LIPA gene. Some LIPA gene products have been discovered to be associated with reduced lysosomal acid lipase (LAL) activity.