The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Apr. 27, 2018
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventor:
Stacey L. Halum, Indianapolis, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/34 (2015.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01); A61P 43/00 (2006.01); A61K 35/30 (2015.01); C12N 5/077 (2010.01); A61K 38/18 (2006.01); A61K 31/221 (2006.01);
U.S. Cl.
CPC ...
A61K 35/34 (2013.01); A61K 35/30 (2013.01); A61P 21/00 (2018.01); A61P 25/00 (2018.01); A61P 43/00 (2018.01); C12N 5/0658 (2013.01); A61K 31/221 (2013.01); A61K 38/1883 (2013.01); A61K 2300/00 (2013.01); C12N 2501/805 (2013.01);
Abstract
This invention relates to a method for repairing and reconstructing a damaged or non-functional muscle, in particular to a method and a tool kit using in vitro primed motor endplate-expressing muscle progenitor cells (MPCs) to promote innervation of the damaged or non-functional muscle using an agent without any genetic manipulation. This method is particularly useful for repairing or reconstructing damaged or non-functional head and neck muscles, and urinary detrusor bladder muscle.