The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2022

Filed:

Feb. 24, 2020
Applicant:

Warsaw Orthopedic, Inc., Warsaw, IN (US);

Inventors:

Roger E. Harrington, Collierville, TN (US);

Jerbrena C. Jacobs, Hernando, MS (US);

Assignee:

Warsaw Orthopedic, Inc., Warsaw, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 41/00 (2006.01); A61K 31/00 (2006.01); G01N 33/74 (2006.01); A61K 31/575 (2006.01);
U.S. Cl.
CPC ...
A61K 31/575 (2013.01); G01N 33/743 (2013.01);
Abstract

Assay methods for determining purity of a sample of a sterol are provided. These methods include providing an HPLC eluent including a sterol, other compounds related to the sterol and a mobile volatile phase; generating an aerosol of liquid droplets from the HPLC eluent; drying the liquid droplets to obtain residue particles of the sterol; contacting the residue particles of the sterol with an ion stream which applies a size-dependent electrical charge to each of the residue particles to generate an electrical signal and measuring the electrical signal to determine the purity of the sterol in the sample. The sterol can be OXY133 or OXY133 monohydrate.


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