The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2022
Filed:
Sep. 25, 2018
Applicant:
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Inventors:
Timothy A. Chan, Cortlandt Manor, NY (US);
Diego Chowell Puente, New York, NY (US);
Robert M. Samstein, New York, NY (US);
Luc Morris, New York, NY (US);
Assignee:
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); G16H 50/30 (2018.01); A61P 35/00 (2006.01); C12Q 1/6827 (2018.01); C12Q 1/6881 (2018.01); C12Q 1/6886 (2018.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61K 39/395 (2013.01); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); C07K 16/2896 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6881 (2013.01); C12Q 1/6886 (2013.01); G16H 50/30 (2018.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/80 (2018.08); A61K 2039/812 (2018.08); A61K 2039/86 (2018.08); A61K 2039/868 (2018.08); A61K 2039/876 (2018.08); C07K 2317/76 (2013.01);
Abstract
The present invention encompasses the discovery that the likelihood of a favorable response to cancer immunotherapy for a wide range of different cancers can be predicted through definition of a tumor mutational load threshold for the tumor (and/or the relevant immunotherapy).