The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2022
Filed:
Jun. 25, 2020
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Haifeng Tang, Metuchen, NJ (US);
Weiguo Liu, Princeton Junction, NJ (US);
Fa-Xiang Ding, Staten Island, NY (US);
Wanying Sun, Edison, NJ (US);
Yi Zang, Princeton, NJ (US);
Weidong Pan, Hillsborough, NJ (US);
Anthony Ogawa, Mateo, CA (US);
Linda Brockunier, Orange, NJ (US);
Xianhai Huang, Warren, NJ (US);
Hongwu Wang, Westfield, NJ (US);
Rudrajit Mal, Edison, NJ (US);
Tesfaye Biftu, Freehold, NJ (US);
Min Park, Morristown, NJ (US);
Yan Guo, Westfield, NJ (US);
Jinlong Jiang, Scotch Plains, NJ (US);
Helen Y. Chen, Marlboro, NJ (US);
Christopher W. Plummer, Cranford, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention relates to biaryl monobactam compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein X, Y, Z, A, Q, A, M, W, Rand Rare as defined herein. The present invention also relates to compositions which comprise a biaryl monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.