The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2022
Filed:
Apr. 30, 2020
Applicant:
Afferent Pharmaceuticals, Inc., San Mateo, CA (US);
Inventors:
Prabha Ibrahim, San Mateo, CA (US);
Ronald Charles Hawley, San Mateo, CA (US);
Anthony P. Ford, Palo Alto, CA (US);
Steven A. Smith, San Mateo, CA (US);
Assignee:
AFFERENT PHARMACEUTICALS, INC., San Mateo, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/48 (2006.01); A61K 9/20 (2006.01); A61K 31/191 (2006.01);
U.S. Cl.
CPC ...
C07D 239/48 (2013.01); A61K 9/2095 (2013.01); A61K 31/191 (2013.01);
Abstract
Provided are novel salts and polymorphs of 5-(2,4-diamino-pyrimidin-5-yloxy)-4-isopropyl-2-methoxy-benzenesulfonamide, which are potentially useful for modulating a condition mediated by a P2X3 or P2X2/3 receptor. Also provided are pharmaceutical formulations and methods of administration and dosing of these salts and polymorphs to subjects in need thereof.